A rapid, high-volume cervical screening project using self-sampling and isothermal PCR HPV testing
Objective: Rapid, high-volume screening programs are needed as part of cervical cancer prevention in China.
Methods: In a 5-day screening project in Inner Mongolia, 3345 women volunteered following a community awareness campaign, and self-swabbed to permit rapid HPV testing. Two AmpFire™ HPV detection systems (Atila Biosystems) were sufficient to provide pooled 15-HPV type data within an hour. HPV+ patients had same-day digital colposcopy (DC) performed by 1 of 6 physicians, using the EVA™ system (MobileODT). Digital images were obtained and, after biopsy of suspected lesions for later confirmatory diagnosis, women were treated immediately based on colposcopic impression. Suspected low- grade lesions were offered treatment with thermal ablation (Wisap), and suspected high-grade lesions were treated with LLETZ.
Results: Of 3345 women screened, 624 (18.7%) were HPV+. Of these, 88.5% HPV+ women underwent same-day colposcopy and 78 were treated. Later consensus histology results obtained on 197 women indicated 20 CIN2+, of whom 15 were detected and treated/referred at screening (10 by thermal ablation, 4 by LLETZ, 1 by referral).
Conclusions: Global control of cervical cancer will require both vaccination and screening of a huge number of women. This study illustrates a cervical screening strategy that can be used to screen-and-treat large numbers of women. HPV self-sampling facilitates high-volume screening. Specimens can be tested rapidly, promoting minimal loss-to-follow-up.
Specifically, the AmpFire™ system used in this study is highly portable, simple, rapid (92 specimens per 65 min per unit), and economical. Visual triage can be performed on HPV+ women with a portable digital colposcope that provides magnification, lighting, and a recorded image. Diagnosis and appropriate treatment remain the most subjective elements. The digital image is under study for deep-learning based automated evaluation that could assist the management decision, either by itself or combined with HPV typing.
[The Identification of Acinetobacter baumannii Blood Isolates by MALDI-TOF MS, ARDRA and blaOXA-51-like Gene-Specific Real-Time PCR]
The Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex consists of phenotypically very similar nosocomial species; A.baumannii, Acinetobacter nosocomialis, Acinetobacter pittii, Acinetobacter seifertii and Acinetobacter djikshoorniae and one environmental species A.calcoaceticus. The rapid and accurate identification of the members of Acb complex is critical as these nosocomial pathogens can show differences in antimicrobial susceptibility and clinical outcomes.
The conventional phenotypic methods are slow, unreliable and less efficient for the differentiation of Acb complex species, including the A.baumannii species within the Acb complex. Although various molecular methods are available, such as amplified ribosomal DNA restriction analysis (ARDRA) and blaOXA-51-like gene specific PCR, they are usually inconvenient for the routine diagnostic laboratories. Recently, matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) offers an opportunity for rapid, cost-effective and convenient bacterial identification in routine diagnostic procedures conducted in clinical laboratory. In this study, we aimed to evaluate the diagnosis performance of MALDI-TOF MS system to identify blood isolates of A.baumannii. A total of 180 nonduplicate carbapenem resistant Acb complex (strain numbers; TR1-TR60) and A.baumannii (TR61-TR180) blood isolates were collected from the intensive care units of the three university hospitals in Turkey from January 2016 to December 2016.
All isolates were evaluated by using blaOXA-51-like gene specific real time (Rt-PCR) analysis, ARDRA (restriction enzymes-AluI, CfoI, MboI, MspI, RsaI) method and MALDI-TOF MS (VITEK® MS, bioMérieux, France) system. All the strains except TR10, TR31, TR35 and TR52 were identified as A.baumannii by ARDRA method. Out of 177 of all the isolates, presence of blaOXA-51-like gene was found except for TR10, TR31 and TR52 isolates. However, TR31 without the presence of blaOXA-51-like gene was identified as A.pittii using the ARDRA. Totally 176 isolates which were identified as A.baumannii by both of the methods, ARDRA and Rt-PCR- blaOXA-51-like, were accepted as a reference for the evaluation of the diagnosis performance capacity of the MALDI-TOF MS. Overall, for all 176 isolates tested, the sensitivity obtained with the MALDI-TOF MS were 99.4% with 75% specificity.
The accuracy value of the method was determined as 98.9% for the identification of A.baumannii to the species level. MALDI-TOF MS is increasingly used in diagnostic microbiology for the routine identification of bacteria to the genus, species or subspecies level with high rates of sensitivity and specificity. In future, by expanding the database, MALDI-TOF MS system would possibly become the ideal method for routine diagnostic laboratories that could potentially identify more species and even determine some characteristics of antimicrobial resistance and virulence determinants.
Evaluation of SARS-CoV-2 IgG antibody response in PCR positive patients: Comparison of nine tests in relation to clinical data
SARS-CoV-2 antibody tests are available in various formats, detecting different viral target proteins and antibody subclasses. The specificity and sensitivity of SARS-CoV-2 antibody tests are known to vary and very few studies have addressed the performance of these tests in COVID-19 patient groups at different time points. We here compared the sensitivity and specificity of seven commercial (SNIBE, Epitope, Euroimmun, Roche, Abbott, DiaSorin, Biosensor) and two in-house LIPS assays (LIPS N and LIPS S-RBD) IgG/total Ab tests in serum samples from 97 COVID-19 patients and 100 controls, and correlated the results with the patients’ clinical data and the time-point the test was performed. We found a remarkable variation in the sensitivity of antibody tests with the following performance: LIPS N (91.8%), Epitope (85.6%), Abbott and in-house LIPS S-RBD (both 84.5%), Roche (83.5%), Euroimmun (82.5%), DiaSorin (81.4%), SNIBE (70.1%), and Biosensor (64.9%).
The overall agreement between the tests was between 71-95%, whereas the specificity of all tests was within 98-100%. The correlation with patients’ clinical symptoms score ranged from strongest in LIPS N (ρ = 0.41; p<0.001) to nonsignificant in LIPS S-RBD. Furthermore, the time of testing since symptom onset had an impact on the sensitivity of some tests. Our study highlights the importance to consider clinical symptoms, time of testing, and using more than one viral antigen in SARS-CoV-2 antibody testing. Our results suggest that some antibody tests are more sensitive for the detection of antibodies in early stage and asymptomatic patients, which may explain the contradictory results of previous studies and should be taken into consideration in clinical practice and epidemiological studies.
HAV Real Time RT-PCR Kit |
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GWB-LRB012 | GenWay Biotech | 25 tests | Ask for price |
HCV Real Time RT-PCR Kit |
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GWB-LRB025 | GenWay Biotech | 25 tests | Ask for price |
HCV Real Time RT-PCR Kit |
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GWB-LRB026 | GenWay Biotech | 25 tests | Ask for price |
HDV Real Time RT-PCR Kit |
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GWB-LRB029 | GenWay Biotech | 25 tests | Ask for price |
HDV Real Time RT-PCR Kit |
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GWB-LRB030 | GenWay Biotech | 25 tests | Ask for price |
HGV Real Time RT-PCR Kit |
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GWB-LRB039 | GenWay Biotech | 25 tests | Ask for price |
HGV Real Time RT-PCR Kit |
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GWB-LRB040 | GenWay Biotech | 25 tests | Ask for price |
HCV/HBV/HIV1/HIV2 Real-TM Real Time PCR kit |
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V62-100FRT | Sacace Biotechnologies | 100 | EUR 1560.88 |
HCMV Real Time PCR Kit |
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GWB-LRB009 | GenWay Biotech | 25 tests | Ask for price |
HCMV Real Time PCR Kit |
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GWB-LRB010 | GenWay Biotech | 25 tests | Ask for price |
HIV DNA Real-TM Qual Real Time PCR Test for detection of proviral HIV DNA |
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R-V1-D | Sacace Biotechnologies | 100 | EUR 1471.5 |
HEV IV Real Time RT-PCR Kit |
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GWB-LRB031 | GenWay Biotech | 25 tests | Ask for price |
HEV IV Real Time RT-PCR Kit |
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GWB-LRB032 | GenWay Biotech | 25 tests | Ask for price |
ONE STEP RT-PCR REAL TIME KIT |
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MBT128-10R | EWC Diagnostics | 1 unit | EUR 37.4 |
Description: ONE STEP RT-PCR REAL TIME KIT |
ONE STEP RT-PCR REAL TIME KIT |
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MBT128-25R | EWC Diagnostics | 1 unit | EUR 89.72 |
Description: ONE STEP RT-PCR REAL TIME KIT |
ONE STEP RT-PCR REAL TIME KIT |
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MBT128-2X50R | EWC Diagnostics | 1 unit | EUR 314.51 |
Description: ONE STEP RT-PCR REAL TIME KIT |
ONE STEP RT-PCR REAL TIME KIT |
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MBT128-50R | EWC Diagnostics | 1 unit | EUR 165.56 |
Description: ONE STEP RT-PCR REAL TIME KIT |
HCV Genetype Real Time RT-PCR Kit |
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GWB-LRB027 | GenWay Biotech | 25 tests | Ask for price |
HCV Genetype Real Time RT-PCR Kit |
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GWB-LRB028 | GenWay Biotech | 25 tests | Ask for price |
RV Real Time RT-PCR Detection kit |
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TRI-L02M1 | TRI Biotech | 32T | EUR 705.6 |
RV Real Time RT-PCR Detection kit |
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TRI-L02S1 | TRI Biotech | 16T | EUR 378 |
HLA B27 Real-TM Real Time PCR kit |
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R116-50FRT | Sacace Biotechnologies | 48 | EUR 627.84 |
Measles Virus Real Time RT-PCR Kit |
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GWB-LRB043 | GenWay Biotech | 25 tests | Ask for price |
Measles Virus Real Time RT-PCR Kit |
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GWB-LRB044 | GenWay Biotech | 25 tests | Ask for price |
Rubella Virus Real Time RT-PCR Kit |
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GWB-LRB045 | GenWay Biotech | 25 tests | Ask for price |
Rubella Virus Real Time RT-PCR Kit |
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GWB-LRB046 | GenWay Biotech | 25 tests | Ask for price |
FCV Real Time RT-PCR Detection kit |
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TRI-L14M1 | TRI Biotech | 32T | EUR 705.6 |
FCV Real Time RT-PCR Detection kit |
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TRI-L14S1 | TRI Biotech | 16T | EUR 378 |
FIV Real Time RT-PCR Detection kit |
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TRI-L22M1 | TRI Biotech | 32T | EUR 705.6 |
FIV Real Time RT-PCR Detection kit |
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TRI-L22S1 | TRI Biotech | 16T | EUR 378 |
FIPV Real Time RT-PCR Detection kit |
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TRI-L03M1 | TRI Biotech | 32T | EUR 453.6 |
FIPV Real Time RT-PCR Detection kit |
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TRI-L03S1 | TRI Biotech | 16T | EUR 252 |
CPIV Real Time RT-PCR Detection kit |
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TRI-L07M1 | TRI Biotech | 32T | EUR 453.6 |
CPIV Real Time RT-PCR Detection kit |
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TRI-L07S1 | TRI Biotech | 16T | EUR 252 |
CSFV Real Time RT-PCR Detection kit |
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TRI-L28M1 | TRI Biotech | 48T | EUR 1008 |
CSFV Real Time RT-PCR Detection kit |
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TRI-L28S1 | TRI Biotech | 24T | EUR 529.2 |
PEDV Real Time RT-PCR Detection kit |
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TRI-L34M1 | TRI Biotech | 48T | EUR 1008 |
PEDV Real Time RT-PCR Detection kit |
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TRI-L34S1 | TRI Biotech | 24T | EUR 529.2 |
CP&MP Real Time PCR Kit |
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GWB-LRB005 | GenWay Biotech | 25 tests | Ask for price |
CP&MP Real Time PCR Kit |
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GWB-LRB006 | GenWay Biotech | 25 tests | Ask for price |
MRSA Quant Real-TM Real Time PCR kit |
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B78-100FRT | Sacace Biotechnologies | 100 | EUR 784.8 |
Chikungunya Virus Real Time RT-PCR Kit |
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GWB-LRB001 | GenWay Biotech | 25 tests | Ask for price |
Chikungunya Virus Real Time RT-PCR Kit |
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GWB-LRB002 | GenWay Biotech | 25 tests | Ask for price |
Yersinia pestis Real-TM Real Time PCR kit |
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B79-50FRT | Sacace Biotechnologies | 50 | EUR 627.84 |
Monkeypox Virus Real Time PCR Kit |
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YJC70115NW-25T | Jiangsu Bioperfectus Technologies | 25 tests/kit | Ask for price |
Description: The Bioperfectus Monkeypox Virus Real Time PCR Kit is an in vitro diagnostic test, based on real-time PCR technology, for the detection of DNA from the Monkeypox virus. Specimens can be obtained from human serum, lesion exudate samples and scab. BSL-2 facilities with standard BSL-2 work practices may be used for the test of t he Monkeypox virus. |
Monkeypox Virus Real Time PCR Kit |
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ZD-0076-01 | Gentaur Genprice | 25 tests/kit | Ask for price |
Description: Monkeypox virus is the virus that causes the disease monkeypox in both humans and animals. Monkeypox virus is an Orthopoxvirus, a genus of the family Poxviridae that contains other viral species that target mammals. The virus is mainly found in tropical rainforest regions of central and West Africa. The primary route of infection is thought to be contact with the infected animals or their bodily fluids. The genome is not segmented and contains a single molecule of linear double-stranded DNA, 185000 nucleotides long. The Monkeypox Virus real time PCR Kit contains a specific ready-to-use system for the detection of the Monkeypox Virusthrough polymerase chain reaction (PCR) in the real-time PCR system. The master contains reagents and enzymes for the specific amplification of the Monkeypox Virus DNA. Fluorescence is emitted and measured by the real time systems ́ optical unit during the PCR. The detection of amplified Monkeypox Virus DNA fragment is performed in fluorimeter channel 530nm with the fluorescent quencher BHQ1. DNA extraction buffer is available in the kit and serum or lesion exudate samples are used for the extraction of the DNA. In addition, the kit contains a system to identify possible PCR inhibition by measuring the 560nm fluorescence of the internal control (IC). An external positive control defined as 1×10^7 copies/ml is supplied which allow the determination of the gene load. |
Monkeypox Virus Real Time PCR Kit |
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ZD-0076-02 | Gentaur Genprice | 25 tests/kit | Ask for price |
Description: Monkeypox virus is the virus that causes the disease monkeypox in both humans and animals. Monkeypox virus is an Orthopoxvirus, a genus of the family Poxviridae that contains other viral species that target mammals. The virus is mainly found in tropical rainforest regions of central and West Africa. The primary route of infection is thought to be contact with the infected animals or their bodily fluids.The genome is not segmented and contains a single molecule of linear double-stranded DNA, 185000 nucleotides long.The Monkeypox Virus real time PCR Kit contains a specific ready-to-use system for the detection of the Monkeypox Virusthrough polymerase chain reaction (PCR) in the real-time PCR system. The master contains reagents and enzymes for the specific amplification of theMonkeypox VirusDNA. Fluorescence is emitted and measured by the real time systems ́ optical unit during the PCR. The detection of amplified Monkeypox Virus DNA fragment is performed in fluorimeter channelFAM with the fluorescent quencher BHQ1. DNA extraction buffer is available in the kit and serum or lesion exudate samples are used for the extraction of the DNA. In addition, the kit contains a system to identify possible PCR inhibition by measuring the HEX/VIC/JOE fluorescence of the internal control (IC). An external positive control defined as 1×107copies/ml is supplied which allow the determination of the gene load. |
Monkeypox Virus Real Time PCR Kit |
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PDPS-AR064 | Creative Biogene | 1 unit | Ask for price |
Description: Creative Biogene Monkeypox Virus Real Time PCR Kit is used for the detection of monkeypox Virus in serum or lesion exudate samples by using real time PCR systems. Monkeypox virus (MPV) is a double-stranded DNA, zoonotic virus and a species of the genus Orthopoxvirus in the family Poxviridae. It is one of the human orthopoxviruses that includes variola (VARV), cowpox (CPX), and vaccinia (VACV) viruses. The kit contains a specific ready-to-use system for the detection of the monkeypox Virus. Fluorescence is emitted and measured by the real time systems' optical unit during the PCR. |
VetAlert Johnes Real Time PCR Kit |
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TC-9828-100 | Tetracore | 100 rxns | EUR 460 |
Staphilococcus aureus Real-TM Real Time PCR kit |
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B1772-96FRT | Sacace Biotechnologies | 96 | EUR 562.44 |
HBV Quantitative Real Time PCR Kit |
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GWB-LRB013 | GenWay Biotech | 25 tests | Ask for price |
HBV Quantitative Real Time PCR Kit |
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GWB-LRB014 | GenWay Biotech | 25 tests | Ask for price |
Toxoplasma Gondii Real Time PCR Kit |
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GWB-LRB049 | GenWay Biotech | 25 tests | Ask for price |
Toxoplasma Gondii Real Time PCR Kit |
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GWB-LRB050 | GenWay Biotech | 25 tests | Ask for price |
HEV I & III Real Time RT-PCR Kit |
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GWB-LRB033 | GenWay Biotech | 25 tests | Ask for price |
HEV I & III Real Time RT-PCR Kit |
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GWB-LRB034 | GenWay Biotech | 25 tests | Ask for price |
CHV Real Time PCR Detection kit |
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TRI-L09M1 | TRI Biotech | 32T | EUR 453.6 |
CHV Real Time PCR Detection kit |
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TRI-L09S1 | TRI Biotech | 16T | EUR 252 |
PCVⅡ Real Time PCR Detection kit |
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TRI-L29M1 | TRI Biotech | 48T | EUR 705.6 |
PCVⅡ Real Time PCR Detection kit |
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TRI-L29S1 | TRI Biotech | 24T | EUR 378 |
ASFV Real Time PCR Detection kit |
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TRI-L04M1C | TRI Biotech | 48T | EUR 554.4 |
ASFV Real Time PCR Detection kit |
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TRI-L04S1C | TRI Biotech | 24T | EUR 302.4 |
HEV General Type Real Time RT-PCR Kit |
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GWB-LRB037 | GenWay Biotech | 25 tests | Ask for price |
HEV General Type Real Time RT-PCR Kit |
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GWB-LRB038 | GenWay Biotech | 25 tests | Ask for price |
BioRT Real Time RT-PCR Kit(SYBR Green) |
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TRI-B33M1 | TRI Biotech | 100T | EUR 1058.4 |
BioRT Real Time RT-PCR Kit(SYBR Green) |
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TRI-B33S1 | TRI Biotech | 50T | EUR 554.4 |
Babesia Real Time PCR Detection kit |
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TRI-L20M1 | TRI Biotech | 32T | EUR 453.6 |
Babesia Real Time PCR Detection kit |
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TRI-L20S1 | TRI Biotech | 16T | EUR 252 |
Giardia Real Time PCR Detection kit |
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TRI-L26M1 | TRI Biotech | 32T | EUR 453.6 |
Giardia Real Time PCR Detection kit |
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TRI-L26S1 | TRI Biotech | 16T | EUR 252 |
Oncogenetics BRCA Panel Real-TM Real Time PCR kit |
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R-27-P-48FRT | Sacace Biotechnologies | 48 | EUR 1907.5 |
Brucella Real Time PCR Detection kit |
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TRI-L24M1 | TRI Biotech | 32T | EUR 453.6 |
Brucella Real Time PCR Detection kit |
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TRI-L24S1 | TRI Biotech | 16T | EUR 252 |
Chlamydia Real Time PCR Detection kit |
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TRI-L15M1 | TRI Biotech | 32T | EUR 453.6 |
Chlamydia Real Time PCR Detection kit |
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TRI-L15S1 | TRI Biotech | 16T | EUR 252 |
Human Lung Cancer PCR Primer Library |
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HLUCPL-I | Real Time Primers | 1 set | EUR 657.6 |
Human Schwann Cell PCR Primer Library |
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HSCH-I | Real Time Primers | 1 set | EUR 657.6 |
Leptospira Real Time PCR Detection kit |
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TRI-L13M1 | TRI Biotech | 32T | EUR 453.6 |
Leptospira Real Time PCR Detection kit |
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TRI-L13S1 | TRI Biotech | 16T | EUR 252 |
Mycoplasma Real Time PCR Detection kit |
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TRI-L16M1 | TRI Biotech | 32T | EUR 453.6 |
Mycoplasma Real Time PCR Detection kit |
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TRI-L16S1 | TRI Biotech | 16T | EUR 252 |
Ehrilichia Real Time PCR Detection kit |
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TRI-L25M1 | TRI Biotech | 32T | EUR 453.6 |
Ehrilichia Real Time PCR Detection kit |
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TRI-L25S1 | TRI Biotech | 16T | EUR 252 |
Edwardsiella Real Time PCR Detection kit |
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TRI-N14M1 | TRI Biotech | 32T | EUR 491.4 |
Edwardsiella Real Time PCR Detection kit |
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TRI-N14S1 | TRI Biotech | 16T | EUR 289.8 |
PRRSV Universal Real Time RT-PCR Detection kit |
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TRI-L33M1 | TRI Biotech | 48T | EUR 1008 |
PRRSV Universal Real Time RT-PCR Detection kit |
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TRI-L33S1 | TRI Biotech | 24T | EUR 529.2 |
Chlamydia Pheumoniae (CP) Real Time PCR Kit |
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GWB-LRB003 | GenWay Biotech | 25 tests | Ask for price |
Chlamydia Pheumoniae (CP) Real Time PCR Kit |
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GWB-LRB004 | GenWay Biotech | 25 tests | Ask for price |
PRV (gE) Real Time PCR Detection kit |
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TRI-L30M1 | TRI Biotech | 48T | EUR 705.6 |
PRV (gE) Real Time PCR Detection kit |
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TRI-L30S1 | TRI Biotech | 24T | EUR 378 |
COMT Val158Met SNP-Screen Real-TM Real Time PCR kit |
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T01352-50-T | Sacace Biotechnologies | 60 | EUR 538.46 |
FHV-1 Real Time PCR Detection kit |
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TRI-L01M1 | TRI Biotech | 32T | EUR 453.6 |
FHV-1 Real Time PCR Detection kit |
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TRI-L01S1 | TRI Biotech | 16T | EUR 252 |
BP/MP/CP Multiplex Real Time PCR Kit |
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GWB-LRB007 | GenWay Biotech | 25 tests | Ask for price |
BP/MP/CP Multiplex Real Time PCR Kit |
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GWB-LRB008 | GenWay Biotech | 25 tests | Ask for price |
Fcov and Ccov Real Time RT-PCR Detection kit |
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TRI-L11M1 | TRI Biotech | 32T | EUR 705.6 |
Fcov and Ccov Real Time RT-PCR Detection kit |
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TRI-L11S1 | TRI Biotech | 16T | EUR 378 |
Vibrio Harveyi Real Time PCR Detection Kit |
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TRI-N04M1 | TRI Biotech | 32T | EUR 453.6 |
Vibrio Harveyi Real Time PCR Detection Kit |
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TRI-N04S1 | TRI Biotech | 16T | EUR 252 |
[Evaluation of SARS-CoV-2 PCR Positive Cases in the Pediatric Emergency Department]
In December 2019, a previously unknown type of coronavirus was detected in China and named as “severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)”. The World Health Organization has named the SARS-CoV-2 related as coronavirus disease-2019 (COVID-19) and declared it as a pandemic. There is a limited data about the COVID-19 disease for the pediatric patients. In this study, it was aimed to evaluate the epidemiological, clinical, laboratory and radiologic findings, treatment and clinical outcomes of patients admitted to the pediatric emergency department with the suspicion of COVID-19. Between March 11 and June 16, 2020, patients aged between 1 month-18 years admitted to the pediatric emergency department and who have an indication for sampling for the polymerase chain reaction (PCR) method with the suspicion of COVID-19 according to the current guidelines published by the Ministry of Health were included in the study. The demographic characteristics, symptoms, durations and the history of contact with the suspected/definite COVID-19 cases were questioned in the patients with positive results. Physical examination, laboratory and imaging data of the patients were recorded. According to clinical severity, patients were divided into five groups.
Treatment methods, ward/intensive care unit admission, length of stay at hospital, and prognosis were recorded. Of the 237 patients included in the study, 45 (18.9%) of the samples were positive and 192 (81.1%) were negative. There was a history of contact with COVID-19 positive case in 38 (85.6%) of COVID-19 PCR positive patients. The mean time for onset of symptoms after contact was 3.5 ± 1.7 days. Twenty-one of the patients (46.6%) were asymptomatic and the most common symptom was fever (34.1%) and cough (27.3%). Of the patients whose laboratory tests were requested, lymphopenia wasdetected in 50% and 52.3% of procalcitonin, 23.5% of C-reactive protein and 64.7% of D-dimer values were found to be high.
Chest radiography was obtained from 45.4% of the patients; 90.0% were evaluated as normal, bronchovascular change, pleural effusion and consolidation were detected in one of each (5.0%) patient. Thorax computed tomography (CT) was obtained from 4 (9.0%) patients. One patient had normal CT findings, two patients had consolidation, one patient had peripheral ground-glass appearance and one patient had pleural effusion. Antibiotics were started in 38.6% of the patients and the most commonly used antibiotic was azithromycin (34.1%). Oseltamivir was started in one (2.3%) patient, and 10 (24.7%) patients were treated with hydroxychloroquine.
There were no serious and critical cases according to the clinical severity. Pediatric patients constitute a small part of COVID-19 individuals in the community, and a significant part of them are asymptomatic, and patients who are symptomatic present with a mild clinic. In our study, most of the patients had a history of contact with COVID-19 positive cases, therefore, it should be questioned when evaluating a pediatric patient. There were no specific findings for COVID-19 positive patients in terms of laboratory and radiology.
13 mm Diameter Solid Titanium Tip |
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0-120-0011 | Biologics | 13 mm | EUR 533 |
19 mm Diameter Tapped Titanium Tip |
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0-120-0012 | Biologics | 19 mm | EUR 639 |
19 mm Diameter Solid Titanium Tip |
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0-120-0013 | Biologics | 19 mm | EUR 570 |
25 mm Diameter Tapped Titanium Tip |
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0-120-0014 | Biologics | 25 mm | EUR 682 |
25 mm Diameter Solid Titanium Tip |
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0-120-0015 | Biologics | 25 mm | EUR 614 |
Flat Replaceable Tips 13 mm Diameter Flat Titanium Tip |
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0-120-0016 | Biologics | 13 mm | EUR 86 |
Description: use with corresponding Tapped Tips and Tapped Extender Tips |
Flat Replaceable Tips 19 mm Diameter Flat Titanium Tip |
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0-120-0017 | Biologics | 19 mm | EUR 92 |
Description: use with corresponding Tapped Tips and Tapped Extender Tips |
Flat Replaceable Tips 25 mm Diameter Flat Titanium Tip |
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0-120-0018 | Biologics | 25 mm | EUR 100 |
Description: use with corresponding Tapped Tips and Tapped Extender Tips |
Titanium Cup Tip, 250 ml |
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0-120-0019 | Biologics | 250 ml | EUR 1377 |
Description: includes Interface Washers |
Microtube Tray, 8 Position (for 250 ml Cup Tip) |
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0-120-0021 | Biologics | each | EUR 113 |
Description: includes Interface Washers |
Continuous Flow Chamber |
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0-120-0026 | Biologics | each | EUR 774 |
Description: includes Interface Washers |
Interface Washers 1.5” Diameter, 5/Pkg |
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0-120-003 | Biologics | 1.5'' Diameter | EUR 31 |
13 mm Diameter Solid Titanium Extender Tip |
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0-120-0032 | Biologics | 13 mm | EUR 301 |
13 mm Diameter Tapped Titanium Extender Tip |
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0-120-0033 | Biologics | 13 mm | EUR 362 |
19 mm Diameter Solid Titanium Extender Tip |
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0-120-0034 | Biologics | 19 mm | EUR 315 |
19 mm Diameter Tapped Titanium Extender Tip |
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0-120-0035 | Biologics | 19 mm | EUR 375 |
25 mm Diameter Solid Titanium Extender Tip |
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0-120-0036 | Biologics | 25 mm | EUR 328 |
25 mm Diameter Tapped Titanium Extender Tip |
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0-120-0037 | Biologics | 25 mm | EUR 389 |
KoldPod, 1.5ml Micro Tube |
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0-120-0038 | Biologics | 1.5 ml | EUR 152 |
Description: Thermo conductive tube pods |
KoldPod, 15ml Conical Tube |
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0-120-0039 | Biologics | 15 ml | EUR 275 |
Description: Thermo conductive tube pods |
KoldPod, 50ml Conical Tube |
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0-120-0040 | Biologics | 50 ml | EUR 290 |
Description: Thermo conductive tube pods |
Model 150 V/T Ultrasonic Homogenizer |
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0-121-0002 | Biologics | 210-240V/50-60Hz | EUR 2920 |
Description: Delivers up to 150 Watts of ultrasonic power to the Titanium Tip. The Timer and Duty Cycle function increase preciosion in sample processing processing. |
Model 300 V/T Ultrasonic Homogenizer |
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0-122-0002 | Biologics | 210-240V/50-60Hz | EUR 3520 |
Description: Delivers up to 300 Watts of ultrasonic power to the Titanium Tip. The Timer and Duty Cycle function increase preciosion in sample. |
SONABOZ Sound Abating Chamber |
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0-125-0001 | Biologics | each | EUR 1020 |
Description: Reduces cavitational sound emitted during processing. |
Model 3000 Ultrasonic Homogenizer |
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0-127-0002 | Biologics | 210-240V/50-60Hz | EUR 4120 |
Description: Delivers up to 300 Watts of ultrasonic power to the Titanium Tip and includes an intergrated Sound Abating Chmaber to reduce cavitational sound emitted during processing. The Timer and Duty Cycle function increase preciosion in sample. |
Model 3000MP Ultrasonic Homogenizer |
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0-128-0002 | Biologics | 210-240V/50-60Hz | EUR 4720 |
Description: Delivers up to 300 Watts of ultrasonic power to the Titanium Tip with preciosion control from a microprocessor and a graphical user interface displayed on a large (145 mm) LCD display. The integrated Sound Abating Chamber reduces cavitational sound emitted during processing. |
OMNICON® Zone Reader, 210-240V/50-60Hz |
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0-131-0002 | Biologics | 210-240V/50-60Hz | EUR 35200 |
Description: Designed to Perform multi-plate Assays on round 90/100mm Petri Dishes. The integrated LED illumination system provides transmitted light for brightfield and darkfield illumination of transparent media. |
OMNI-Noculator Peni Cylinder Filler, 210-240V/50-60Hz |
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0-134-0002 | Biologics | 210-240V/50-60Hz | EUR 32200 |
Description: A robotic liquid handling system designed to dispense Peni Cylinders and fill Peni Cylinders with the corresponding antibiotic liquid sample. |
Peni Cylinder Dispenser with Manual Hopper |
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0-144-0002 | Biologics | each | EUR 5406 |
Description: Dispenser can be configured to dispense 4 or 6 Peni Cylinders onto a petri dish. |
Peni Cylinder Dispenser with Motorized Hopper, 100-240V/50-60Hz |
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0-144-0003 | Biologics | 100-240V/50-60Hz | EUR 6254 |
Description: The motorized hopper can be configured to dispense 4 or 6 Peni Cylinders onto a petri Dispenser can be disassembled for disinfection. |
Stainless Steel Peni Cylinder with Flat Face |
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0-144-0005 | Biologics | 6mm I.D. x 8mm O.D. x 10mm Long | EUR 399 |
Description: sold in packages of 100 pieces |
Stainless Steel Peni Cylinder with Chamfered Face |
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0-144-0006 | Biologics | 6mm I.D. x 8mm O.D. x 10mm Long | EUR 412 |
Description: sold in packages of 100 pieces |
Custom development of ELISAs for other species or antibody isotypes not listed in the catalog. Custom testing of samples for IgG/IgM/IgA or total (IgG+IgM+IgA) |
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000-CUS | Alpha Diagnostics | Custom | EUR 602 |
Alpha-Bungarotoxin, CF®405S, 500 ug |
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00002 | Biotium | 1UG | EUR 527 |
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Alpha-bungarotoxin, CF405s |
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00002 | Cusabio | 500uG | EUR 594 |
Description: Minimum order quantity: 1 unit of 500uG |
Alpha-Bungarotoxin, CF®405S, 500 ug |
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00002-1 | Biotium | EA | EUR 527 |
Alpha-Bungarotoxin, CF®405S 100ug |
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00002-100ug | Biotium | 100uG | EUR 132 |
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Alpha-Bungarotoxin, CF®680R, 500 ug |
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9-00003 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Alpha-Bungarotoxin, CF®680R, 500 ug |
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00003-1 | Biotium | EA | EUR 527 |
Alpha-Bungarotoxin, CF®680R 100ug |
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9-00003 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Alpha-Bungarotoxin, CF®640R, 500 ug |
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9-00004 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Alpha-Bungarotoxin, CF®640R, 500 ug |
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00004-1 | Biotium | EA | EUR 527 |
Alpha-Bungarotoxin, CF®640R 100ug |
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9-00004 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Alpha-Bungarotoxin, CF®488A, 500 ug |
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9-00005 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Alpha-Bungarotoxin, CF®488A, 500 ug |
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00005-1 | Biotium | EA | EUR 527 |
Alpha-Bungarotoxin CF®488A 100ug |
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9-00005 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Alpha-Bungarotoxin, CF®568, 500 ug |
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9-00006 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Alpha-Bungarotoxin, CF®568, 500 ug |
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00006-1 | Biotium | EA | EUR 527 |
Alpha-Bungarotoxin, CF®568 100ug |
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9-00006 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Alpha-Bungarotoxin, CF®594, 500 ug |
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9-00007 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Alpha-Bungarotoxin, CF®594, 500 ug |
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00007-1 | Biotium | EA | EUR 527 |
Alpha-Bungarotoxin CF®594 100ug |
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9-00007 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Alpha-Bungarotoxin, CF®633, 500 ug |
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9-00009 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Alpha-Bungarotoxin, CF®633, 500 ug |
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00009-1 | Biotium | EA | EUR 527 |
Alpha-Bungarotoxin, CF®633 100ug |
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9-00009 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
SARS-CoV-2 Indicator Cell Line for RNA Replication - GFP Reporter only |
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0001-PP-001 | IBT Bioservices | 1 cell line (can order x amount) | EUR 12000 |
Description: SARS-CoV-2 GFP reporter cell line using HEK293T (ACE2/TMPRSS2) cells |
Alpha-Bungarotoxin, 1 mg |
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00010-1 | Biotium | 1MG | EUR 193 |
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Alpha-Bungarotoxin, 1 mg |
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00010-1-1 | Biotium | EA | EUR 193 |
Fluorescein-Alpha-Bungarotoxin, 500 ug |
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00011 | Biotium | 500uG | EUR 376 |
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Fluorescein-Alpha-Bungarotoxin, 500 ug |
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00011-1 | Biotium | EA | EUR 376 |
Tetramethylrhodamine-Alpha-Bungarotoxin, 500 ug |
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00012 | Biotium | 500uG | EUR 394 |
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Tetramethylrhodamine-Alpha-Bungarotoxin, 500 ug |
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00012-1 | Biotium | EA | EUR 394 |
Fluorescein-alpha-bungarotoxin, 10x50ug |
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00013 | Biotium | 10ST | EUR 436 |
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Fluorescein-alpha-bungarotoxin, 10x50ug |
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00013-1 | Biotium | EA | EUR 436 |
Tetramethylrhodamine-A-Bungarotoxin, 10x50 ug |
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00014 | Biotium | 10ST | EUR 494 |
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Tetramethylrhodamine-A-Bungarotoxin, 10x50 ug |
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00014-1 | Biotium | EA | EUR 494 |
Sulforhodamine 101-Alpha-Bungarotoxin, 500 ug |
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00015 | Biotium | 500uG | EUR 494 |
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Sulforhodamine 101-Alpha-Bungarotoxin, 500 ug |
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00015-1 | Biotium | EA | EUR 494 |
Sulforhodamine 101-Alpha-Bungarotoxin, 50 ug |
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00016 | Biotium | 10ST | EUR 560 |
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Sulforhodamine 101-Alpha-Bungarotoxin, 50 ug |
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00016-1 | Biotium | EA | EUR 560 |
Biotin-XX-A-Bungarotoxin, 500 ug |
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00017 | Biotium | 500uG | EUR 455 |
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Biotin-XX-A-Bungarotoxin, 500 ug |
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00017-1 | Biotium | EA | EUR 455 |
Alpha-Bungarotoxin, CF®555, 500 ug |
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9-00018 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Alpha-Bungarotoxin, CF®555, 500 ug |
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00018-1 | Biotium | EA | EUR 527 |
Alpha-Bungarotoxin, CF®555 100ug |
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9-00018 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
Acrylamide, Chemzymes Ultra Pure® |
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00019-100 | Polysciences Europe GmbH | 100g | EUR 101.52 |
Description: 79-06-1 |
Acrylamide, Chemzymes Ultra Pure® |
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00019-500 | Polysciences Europe GmbH | 500g | EUR 270 |
Description: 79-06-1 |
Biotin-cAMP, 1 mg |
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00020 | Biotium | 1MG | EUR 298 |
Description: N/A |
Biotin-cAMP, 1 mg |
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00020-1 | Biotium | 20ST | EUR 298 |
Description: N/A |
Biotin-cAMP, 50 ug |
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00020-1-1 | Biotium | EA | EUR 414 |
Biotin-cGMP, 1 mg |
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00021 | Biotium | 1MG | EUR 331 |
Description: N/A |